Down Syndrome Awareness Month – October 16, 2025

Did you know? COVID-19 vaccines are recommended for people with Down syndrome who do not have a contraindication.

While the severity of COVID-19 infection has decreased for many people, it still can be serious for some, especially those with conditions that reduce their ability to fight infections which includes many people with Down syndrome. 

Since the early days of the pandemic, people with Down syndrome were more affected by COVID-19 infection than those without Down syndrome. Multiple research studies have demonstrated that individuals with Down syndrome have a greater risk of more severe COVID-19 infections with more complications.

Studies have demonstrated that COVID-19 vaccines are safe and effective in people with and without Down syndrome. While COVID-19 vaccines have the potential for side effects, studies have found the risks from COVID-19 infection are generally greater than the risks of the vaccine. 

At the Adult Down Syndrome Center, we recommend COVID-19 vaccination (including annual boosters such as the 2025-2026 COVID-19 vaccine) for our patients with Down syndrome who do not have a contraindication. 

Our Resource Library has an article about COVID-19 in people with Down syndrome with information on symptoms, diagnosis, treatment, and prevention. It also includes links to research studies on COVID-19 infection and vaccination in people with Down syndrome.